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Pentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Mixtures: Pentazocine and naloxone, Pentazocine and naloxoneCategories: P-glycoprotein substrates, pentazocine and naloxoneAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.
Synonyms: t-PA, r-tPACategories: Enzymes and Coenzymes, Blood and Blood Forming OrgansCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Pimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADETYohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Synonyms: (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl esterInternational brands: Baron-XStanozolol
go.drugbank.com/drugs/DB06718ApprovedVet approvedStanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. … Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.
Categories: Alimentary Tract and Metabolism, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: อโซลอล 5 มก., STANOBON 10Dulaglutide
go.drugbank.com/drugs/DB09045ApprovedInvestigationalDulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct … therapy to diet and exercise in the management of 2 diabetes (T2DM).
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: TRULICITY® 1.5 MG/0.5 ML, TRULICITY® 0.75 MG/0.5 MLPhytochlorin
go.drugbank.com/drugs/DB19265InvestigationalPhytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: 21h,23h-porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7s,8s)-, 2-porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2.beta.,3-dihydro-3.beta.,7,12,17-tetramethyl-8-vinyl-Vindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnMajor side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Synonyms: 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastineCategories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexMisoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigationalMisoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. … strength and frequency of contractions and decrease cervical tone.
Mixtures: ARTHROTEC 75 MG 10 TABLET, DIFEMIS 50 MG/0.2 MG TABLET, 20 ADETCategories: Prostaglandins E, Synthetic, naproxen and misoprostol