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Entecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Categories: Heterocyclic Compounds, 2-Ring, Hepatitis B virusProducts: HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML, OVAMET 1 MG FILM KAPLI TABLET,30 ADETDPDPE
go.drugbank.com/drugs/DB08861ExperimentalA heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Synonyms: L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide, (D-Pen2,D-Pen5)-EnkephalinTropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnAs a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT3 Receptor AntagonistsProducts: NAVOBAN 5 MG 1 AMPUL, Navoban 5 mg - AmpullenTiclopidine
go.drugbank.com/drugs/DB00208ApprovedIt is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: TICLID 250 MG TABLET, 30 ADET, TICLOCARD 250 MG FILM KAPLI TABLET, 30 ADETCetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH).
Products: CETROTIDE 250 MCG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, CETROTIDE 3 MG ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. … It is not yet approved for use in the U.S., E.U., or Canada.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 5 InhibitorsProducts: ZYDENA 100 MG FILM TABLET, 2 ADET, ZYDENA 100 MG FILM TABLET, 4 ADETAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigational[L38995,A241055] Asciminib received FDA approval on October 29, 2021 (Scemblix, Novartis AG).[L39000] … More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET, AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADETPolyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approved[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. … PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation.
Salts: Polyoxyethylene 23 lauryl etherMixtures: LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 ML, MOVICOL Liquid Orange 13,9 g/25 ml Konzentrat zur Herstellung einer Lösung zum EinnehmenFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalIt was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: FAVERIN 50 MG, FLUVOXAMINA EGNatalizumab
go.drugbank.com/drugs/DB00108ApprovedInvestigationalNatalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. … [A261331] On August 24, 2023, the first biosimilar to natalizumab, natalizumab-sztn, was approved by the FDA.[L48041] Natalizumab was approved by the European Commission on September 22, 2023.
Synonyms: IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMER, IMMUNOGLOBULIN G4 (HUMAN-MOUSE MONOCLONAL AN100226 4-CHAIN ANTI-HUMAN INTEGRIN 4), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL AN100226 LIGHT CHAIN, DIMERProducts: Tysabri 150 mg SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (2 adet), TYSABRI 300 MG I.V. INFUZYON ICIN KONSANTRE COZELTI ICEREN FLAKON, 1 ADET