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Benzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalIt is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. … potency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether, 3α-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octaneBeta-lactamase OXA-10
go.drugbank.com/bio_entities/BE0001274TargetEnzymePseudomonas aeruginosaHydrolyzes both carbenicillin and oxacillin.
Polypeptides: Beta-lactamase OXA-10Ixekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIxekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. … Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons
Categories: Interleukin-17, Amino Acids, Peptides, and ProteinsProducts: COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET, COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETModafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalModafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. … Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil.
Synonyms: 2-((diphenylmethyl)sulfinyl)acetamideCategories: Modafinil and isomer, Metabolic Side Effects of Drugs and SubstancesAcarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes. … Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines.
Categories: metformin and acarbose, Alimentary Tract and MetabolismProducts: GLUCOBAY 50 TABLET 50 mg, ACARBOSA 50 MGCytosolic 10-formyltetrahydrofolate dehydrogenase
go.drugbank.com/bio_entities/BE0000933TargetHumansCytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).
Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDHBone morphogenetic protein 10
go.drugbank.com/bio_entities/BE0010910TargetHumansembryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5.
Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10Ethambutol
go.drugbank.com/drugs/DB00330ApprovedInvestigationalEthambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis. … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.[A229048] Ethambutol was granted FDA approval on 6 November 1967.
Mixtures: RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: MATE 1 Substrates, ethambutol and isoniazidDacomitinib
go.drugbank.com/drugs/DB11963ApprovedInvestigationalDacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: Vizimpro 15 mg Film-Coated Tablets, VİZİMPRO 15 MG FİLM KAPLI TABLET, 30 ADETEtanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigationalIt is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1.
Categories: Amino Acids, Peptides, and ProteinsProducts: ERELZI 50 MG, ENBREL MYCLIC PEN 50 MG ENJ. COZ.ICIN KULLANIMA HAZIR KALEM, 12 ADET