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Neflamapimod
go.drugbank.com/drugs/DB07138InvestigationalNeflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.
Categories: Heterocyclic Compounds, 1-RingIrosustat
go.drugbank.com/drugs/DB02292InvestigationalIrosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Synonyms: 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-SulfamateAS-8112
go.drugbank.com/drugs/DB09207ExperimentalAS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. … It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Categories: Heterocyclic Compounds, 1-Ring, Dopamine D2 Receptor AntagonistsPracinostat
go.drugbank.com/drugs/DB05223InvestigationalData demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors. … Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing.
Categories: Heterocyclic Compounds, 2-RingSerine/threonine-protein kinase haspin
go.drugbank.com/bio_entities/BE0003794TargetHumansSerine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) a...
Synonyms: Germ cell-specific gene 2 proteinHuman Embryonic Stem Cell-derived M Cell
go.drugbank.com/drugs/DB15734InvestigationalCAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. … However, the difference comes with IMRCs displaying a higher quality of consistency, having stronger immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury
Synonyms: M cellsLeukotriene D4
go.drugbank.com/drugs/DB11858InvestigationalLeukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis.
Categories: SRS-ASynonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine, S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycineAAV-CNGB3
go.drugbank.com/drugs/DB18344InvestigationalAAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Nivocasan
go.drugbank.com/drugs/DB12720InvestigationalNivocasan has been used in trials studying the treatment of HCV Infection and Nonalcoholic Steatohepatitis.