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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Amyl Nitrite

    go.drugbank.com/drugs/DB01612
    Approved

    Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use. … Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning.

    Synonyms: n-Amyl nitrite, n-pentyl nitriteProducts: Amylnitrite Glass Cap 5min, Amyl Nitrite Vitrellae Bpc Liq 0.33 Ml/cap
  2. Drug

    Mecobalamin

    go.drugbank.com/drugs/DB03614
    ApprovedInvestigational

    Mixtures: Co-Balamin, Co-VeratrolCategories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  3. Indication

    No feasible standard therapy

    go.drugbank.com/conditions/DBCOND0106309
    Drugs: Catumaxomab · Lenacapavir · Sulprostone
    Synonyms: No feasible standard therapy
  4. Indication

    No resistance to darunavir

    go.drugbank.com/conditions/DBCOND0119794
    Drugs: Tenofovir alafenamide
    Synonyms: No resistance to darunavir
  5. Drug

    Idecabtagene vicleucel

    go.drugbank.com/drugs/DB16665
    ApprovedInvestigational

    [L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA on August 18, 2021.[L51003] … [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from a patient to express a CAR for a tumor specific antigen.

    Synonyms: Anti-BCMA CAR T cellCategories: Receptors, Antigen, T-Cell
  6. Drug

    Methotrimeprazine

    go.drugbank.com/drugs/DB01403
    Approved

    A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. … It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine.

    Synonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine, (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazineCategories: Analgesics, Non-Narcotic, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
  8. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It it suggested that many organic fatty acids exert fungicidal or fungistatic actions. Undecylenic acid also possesses antifungal properties, but is never used on its own for antifungal purposes. … Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone.

    Mixtures: Desenex Medicated Spray-ON Powder, Desenex Medicated Spray-ON PowderProducts: Sally Hansen No More Fungus, Nu Calmar
  9. Indication

    No previous treatment with methotrexate

    go.drugbank.com/conditions/DBCOND0146061
    Drugs: Tocilizumab
    Synonyms: No previous treatment with methotrexate
  10. Indication

    No involvement of nervous system

    go.drugbank.com/conditions/DBCOND0122334
    Drugs: Cyanocobalamin
    Synonyms: No involvement of nervous system