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Displaying results 311 - 320 of 8515 in total
  1. Drug

    Lufotrelvir

    go.drugbank.com/drugs/DB16514
    Investigational

    PF-07304814, developed by Pfizer, was first identified during the SARS outbreak in 2002-2003; it was subsequently shelved as the outbreak was controlled[L31728]. … PF-07304814 is a small molecule prodrug that targets the 3CL<sup>pro</sup> protease (M<sup>pro)</sup>, which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718].

  2. Drug

    Ethinylestradiol

    go.drugbank.com/drugs/DB00977
    ApprovedInvestigational

    Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability. … [A191107] Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884]

  3. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    [A181952] Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748] … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.

    Mixtures: Neo-poly-bac, Ak-poly-bac
  4. Drug

    Chlormerodrin

    go.drugbank.com/drugs/DB00534
    ApprovedWithdrawn

    Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. … It is no longer used and has been replaced with new classes of diuretic drugs.

  5. Drug

    Nitrous oxide

    go.drugbank.com/drugs/DB06690
    ApprovedInvestigationalVet approved

    It is known as "laughing gas" due to the euphoric effects of inhaling it, a property that has led to its recreational use as an inhalant drug. … Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O.

    Mixtures: Alnox Gas, Liqui-med Analgesic GasProducts: Distickstoffmonoxid Westfalen 100% Gas zur medizinischen Anwendung, verflüssigt
  6. Drug

    Zilucoplan

    go.drugbank.com/drugs/DB15636
    ApprovedInvestigational

    [L48701] It was also later approved by the EMA on December 4, 2023, as an add-on treatment for the same condition.[L49131] In July 2024, it was approved by Health Canada for the same indication.

  7. Drug

    Daraxonrasib

    go.drugbank.com/drugs/DB22308
    ApprovedInvestigational

    RAS variants rather than a single mutation. … [L64039] It is a RAS(ON) tri-complex inhibitor that binds cyclophilin A and targets the active, GTP-bound ("ON") state of RAS, suppressing signaling of both wild-type and mutant RAS across the most common

    Categories: RAS GTPase Inhibitors
  8. Indication

    Seasonal Allergic Rhinitis

    go.drugbank.com/conditions/DBCOND0030588
    Drugs: Acrivastine · Azelastine · Beclomethasone dipropionate · Bilastine · Cetirizine · Ciclesonide +22 more
    Synonyms: SARS, SARS Virus
  9. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    Most recently, research has shown that polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 diabetes provided novel insights into the role of … addition to the above, recent review articles have already demonstrated the important role of zinc in the pathophysiology and treatment of affective disorders, plus discussed the potential value of zinc as

    Mixtures: Prim - Royal P.M.T., Luna Vitamin and Mineral Bar for Women
  10. Drug

    Bromotheophylline

    go.drugbank.com/drugs/DB14018
    Approved

    From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. … [A33018] Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980.

    Mixtures: Fem-prin