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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A263026] However, cefixime is not recommended as a first-line of treatment for uncomplicated urogenital, anorectal, or pharyngeal gonorrhea because cefixime does not provide the same bactericidal effect … Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding

    Mixtures: INNOCEF PLUS 400/125 MG SAŞE, 10 ADET, MOLCEF PLUS 400/125 MG FILM KAPLI TABLET, 10 ADETCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Oxolamine

    go.drugbank.com/drugs/DB13216
    Approved

    Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation [L5422]. … Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419].

    Mixtures: KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 ML, KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADETCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Iron polymaltose

    go.drugbank.com/drugs/DB15763
    ApprovedInvestigationalWithdrawn

    Mixtures: FERLOS 100 MG/0.35 MG TABLET, 30 ADET, FERRUM HAUSMANN FORT 100 MG/0,35 MG FİLM TABLET, 30 ADETProducts: FERLOS 20 MG/ML ORAL ÇÖZELTİ, 10 ADET, VEGAFERON 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET
  4. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_. … [L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I.

    Categories: Topoisomerase 1 (TOP1) inhibitors, UGT1A1 Substrates with a Narrow Therapeutic IndexSynonyms: )ethyl)piperidine-1-carboxylate, (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl
  5. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460] … Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.

    Mixtures: OXYCODON/NALOX PUR 10/5MG, OXYCODON/NALOX PUR 10/5MGCategories: Heterocyclic Compounds with 4 or More Rings
  6. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.

    Mixtures: METOPROLOLSUC 1A PL95/12.5, METOPROLOLSUC 1A PL95/12.5Categories: Adrenergic beta-1 Receptor Antagonists, Antihypertensive Agents Indicated for Hypertension
  7. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] … Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.

    Categories: Heterocyclic Compounds, 1-Ring, Antihypertensive Agents Indicated for HypertensionSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
  8. Drug

    Pertuzumab

    go.drugbank.com/drugs/DB06366
    ApprovedInvestigational

    It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal antibody, [trastuzumab], in the treatment of metastatic HER2-positive breast cancer. … Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2).

    Mixtures: PHESGO® 1200 MG/600 MG, PHESGO® 1200 MG/600 MGProducts: PHESGO SOLUTION FOR SUBCUTANEOUS INJECTION 600 MG/600 MG / 10 ML, PHESGO SOLUTION FOR SUBCUTANEOUS INJECTION 1200 MG/600 MG / 15 ML
  9. Drug

    Terazosin

    go.drugbank.com/drugs/DB01162
    ApprovedInvestigational

    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831]. … Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837].

    Mixtures: Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg, Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mgCategories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor Antagonists
  10. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].

    Mixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 GCategories: Heterocyclic Compounds, 1-Ring