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Displaying results 3191 - 3200 of 10000 in total
  1. Pathway

    beta-Ureidopropionase Deficiency

    smpdb.ca/view/SMP0125716
    Disease

    A deficiency in this enzyme results in accumulation of N-carbamyl-beta-amino acids. Symptoms include hypotonia, dystonic movements, scoliosis, microcephaly, and severe developmental delay. … Beta-ureidopropionase deficiency (Beta Alanine-Synthase Deficiency, UPB1, BUP1) is an autosomal recessive disease caused by mutations in the UPB1 gene which codes for beta-ureidopropionase.

    Drugs: L-Glutamine · ATP · Calcium · Magnesium cation · Iron · Zinc +20 more
  2. Pathway

    UMP Synthase Deficiency (Orotic Aciduria)

    smpdb.ca/view/SMP0125717
    Disease

    This disease is characterized by a very large accumulation of orotic acid in the urine, occasionally causing urinary obstruction.

    Drugs: L-Glutamine · ATP · Calcium · Magnesium cation · Iron · Zinc +20 more
  3. Drug

    Haemagglutinin-strain A(H3N2)

    go.drugbank.com/drugs/DB15475
    ApprovedInvestigational

    Mixtures: Afluria Tetra Injektionssuspension in einer FertigspritzeSynonyms: Haemagglutinin-strain A (H3N2), Haemagglutinin-strain A(H3N2)
  4. Drug

    Haemagglutinin-strain A(H1N1)

    go.drugbank.com/drugs/DB15476
    ApprovedInvestigational

    Mixtures: Afluria Tetra Injektionssuspension in einer FertigspritzeSynonyms: Haemagglutinin-strain A (H1N1), Haemagglutinin-strain A(H1N1)
  5. Drug

    Triamterene

    go.drugbank.com/drugs/DB00384
    Approved

    [L6166] It is also found in a combination product with hydrochlorothiazide that is used for the management of hypertension or treatment of edema in patients who develop hypokalemia on hydrochlorothiazide … It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side.

    Synonyms: 6-phenylpteridine-2,4,7-triamineMixtures: DYTIDE H, DYTIDE H
  6. Drug

    Oxazepam

    go.drugbank.com/drugs/DB00842
    Approved

    Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. … as compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism.

    Categories: Heterocyclic Compounds, 2-RingInternational brands: Ox-Pam
  7. Drug

    Nurulimab

    go.drugbank.com/drugs/DB18946
    Investigational

    Nurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in

  8. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    [A249255] First used as an antiseptic and disinfectant in the 1950s, dequalinium is still found in various OTC products to treat conditions of oral infections and inflammation. … [A249255] It is also used in vaginal tablets to treat bacterial vaginosis.[L42190]

    Mixtures: EFISOL-C, JASIMENTH C PASTILLESCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Metrizamide

    go.drugbank.com/drugs/DB01578
    Experimental

    It is also used as a resorbable, non-ionic contrast medium. … Metrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity.

    Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals
  10. Drug

    Brentuximab

    go.drugbank.com/drugs/DB05471
    Investigational

    We are collaborating with the National Cancer Institute (NCI) on three clinical trials of SGN-30 in combination with chemotherapy for the treatment of relapsed Hodgkin lymphoma, front-line ALCL and pediatric … SGN-30 has demonstrated objective antitumor responses as a single agent in phase II clinical trials.