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Orgotein
go.drugbank.com/drugs/DB11444ExperimentalVet approvedHydrogen peroxide can be degraded by catalase. The antioxidant mechanism of SOD is common to most organisms exposed to oxygen. A notable exception is Lactobacillus plantarum. … Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage.
Categories: Analgesics, Non-Narcotic, Antiinflammatory and Antirheumatic Products, Non-SteroidsAC3056
go.drugbank.com/drugs/DB05230ExperimentalAC3056 is a non-peptide antioxidant that acts as an inhibitor of vascular cell adhesion molecule expression originally developed by Aventis Pharmaceuticals. … It as since been acquired by Amylin Pharmaceuticals and has completed phase I trials.
Xylazine
go.drugbank.com/drugs/DB11477InvestigationalVet approved[L42675] Xylazine is sometimes used as an adulterant and combined with opioids and recreational drugs; however, it has no antidote, and the use of [naloxone] has no effect on xylazine.[L42675,L42680] … [A32545] Xylazine is not approved for human use and requires a veterinary licence for its purchase and use.
Poliglusam
go.drugbank.com/drugs/DB11234ApprovedInvestigationalPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. … Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase
Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A251405] Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and to assist in specific surgical procedures such as cystourethroscopy. … [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to aid in visualizing ureter integrity in cystoscopic assessments.[L42600]
Talniflumate
go.drugbank.com/drugs/DB09295Investigationalresearch has now been discontinued [L1402, L1405]. … Phase I trials with talniflumate for the treatment of cystic fibrosis and COPD were completed in August 2001, and phase II trials were performed in Ireland for the treatment of cystic fibrosis but this
Categories: Anti-Inflammatory Agents, Non-SteroidalDG051
go.drugbank.com/drugs/DB05177ExperimentalDG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. … DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation.
Tepoxalin
go.drugbank.com/drugs/DB11466ExperimentalVet approvedIt is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSSynonyms: 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acidCobalt
go.drugbank.com/drugs/DB14574ApprovedWithdrawnDeficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. … It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments.
SR-9011
go.drugbank.com/drugs/DB14014ExperimentalSR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues
Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-