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Displaying results 3191 - 3200 of 10000 in total
  1. Drug

    Difluprednate

    go.drugbank.com/drugs/DB06781
    ApprovedInvestigational

    Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate.

  2. Drug

    Cocamidopropyl betaine

    go.drugbank.com/drugs/DB11350
    Approved

    It is a zwitterionic ammonium compound and fatty acid amide that contains a long hydrocarbon chain and a polar group at each end. … Cocamidopropyl betaine is used as a foam booster in shampoos, emulsifying agent, thickener, antistatic agent and rarely an antiseptic agent.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Ledipasvir

    go.drugbank.com/drugs/DB09027
    Approved

    Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend ledipasvir as a first line

  4. Drug

    Etesevimab

    go.drugbank.com/drugs/DB15897
    Investigational

    Etesevimab (LY-CoV016, also known as JS016) is a fully human and recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor binding domain. … progressing to severe COVID-19:[L40179] this EUA later expanded in December 2021 to include all younger children at high risk, including newborns.

  5. Drug

    Flumethasone

    go.drugbank.com/drugs/DB00663
    ApprovedVet approved

    As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.

  6. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

  7. Drug

    Chlortetracycline

    go.drugbank.com/drugs/DB09093
    ApprovedVet approvedWithdrawn

    He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. … Chlortetracycline is a _tetracycline_ antibiotic, and historically the first member of this class to be identified.

  8. Drug

    Obiltoxaximab

    go.drugbank.com/drugs/DB05336
    Approved

    Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa. … Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin.

  9. Drug

    Pegloticase

    go.drugbank.com/drugs/DB09208
    ApprovedInvestigational

    [A249980] The PEG group also gives pegloticase a lower potential to induce an immune response. … [L42425] Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin.

    Categories: Compounds used in a research, industrial, or household setting
  10. Target

    Elongation factor 1-alpha 1

    go.drugbank.com/bio_entities/BE0004528
    TargetHumans

    Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis (PubMed:26593721, PubMed:26651998, PubMed:36123449, PubMed:362...

    Synonyms: Leukocyte receptor cluster member 7