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Misoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigationalstrength and frequency of contractions and decrease cervical tone. … Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.
Mixtures: Diclofenac Sodium and Misoprostol, Diclofenac Sodium and MisoprostolCategories: naproxen and misoprostol, Alimentary Tract and MetabolismOuabain
go.drugbank.com/drugs/DB01092ApprovedA cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. … It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Deserpidine
go.drugbank.com/drugs/DB01089ApprovedWithdrawnDeserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure … and for the relief of psychotic behavior.
Categories: deserpidine and diureticsFaricimab
go.drugbank.com/drugs/DB15303ApprovedInvestigational[A225985, A225990, A225995, A226000, A226005, A226010] Faricimab was approved by the FDA on January 28, 2022, and is currently marketed under the trademark VABYSMO by Genentech, Inc. … Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization
Categories: Amino Acids, Peptides, and ProteinsLenograstim
go.drugbank.com/drugs/DB13144ApprovedWithdrawnLenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsCalcium levulinate
go.drugbank.com/drugs/DB13800ApprovedThe relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide [L2765]. … This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and soy products with calcium
Categories: Alimentary Tract and MetabolismCipepofol
go.drugbank.com/drugs/DB16295ApprovedInvestigationallabel has since expanded to cover procedural sedation, induction and maintenance of general anesthesia, sedation during mechanical ventilation in the intensive care unit, and - from September 2025 - induction … [L63931] It is indicated only for induction of general anesthesia, with another agent used up for maintenance.
Categories: Hypnotics and SedativesUnoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate....
Categories: Antiglaucoma Preparations and MioticsCarboprost tromethamine
go.drugbank.com/drugs/DB00429ApprovedInvestigationalA nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Categories: Genito Urinary System and Sex HormonesMitotane
go.drugbank.com/drugs/DB00648ApprovedInvestigationalMitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and … It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is used off-label for the management of Cushing's syndrome.[A263016]
Categories: Antineoplastic and Immunomodulating Agents