Search

Displaying results 3201 - 3210 of 8575 in total
  1. Drug

    TAS-106

    go.drugbank.com/drugs/DB06656
    Investigational

    TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].

  2. Drug

    Lutein

    go.drugbank.com/drugs/DB00137
    ApprovedNutraceutical

    Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. … In green plants, xanthophylls act to modulate light energy and serve as non-photochemical quenching agents to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very

  3. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynth...

  4. Drug

    Aprobarbital

    go.drugbank.com/drugs/DB01352
    ExperimentalIllicit

    Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia.

  5. Drug

    MC-1

    go.drugbank.com/drugs/DB05315
    Experimental

    Medicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.

  6. Drug

    ACA 125

    go.drugbank.com/drugs/DB05489
    Investigational

    To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber cell culture system. Positive clinical results are now being reported. … An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies.

  7. Drug

    BMS-908662

    go.drugbank.com/drugs/DB12854
    Investigational

    BMS-908662 has been used in trials studying the treatment of Melanoma and Colorectal Cancer.

  8. Drug

    Protionamide

    go.drugbank.com/drugs/DB12667
    ApprovedInvestigationalWithdrawn

    Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.

  9. Drug

    Tribromsalan

    go.drugbank.com/drugs/DB20138
    ApprovedWithdrawn

    Tribromsalan has a monoisotopic molecular weight of 446.81 Da.

  10. Drug

    Desmoteplase

    go.drugbank.com/drugs/DB04925
    Investigational

    When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. … Desmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1).