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Pemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnPemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
Procaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedA local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeImiglucerase
go.drugbank.com/drugs/DB00053ApprovedInvestigationalThe modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues.
Colistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalCyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the meth...
Products: Costin 25% w/w Premix Powder, LIFE COLI 10%W/W PREMIX POWDERCarmofur
go.drugbank.com/drugs/DB09010ApprovedWithdrawnCarmofur has been known to induce leukoencephalopathy.
Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[L13290,L13296] A subcutaneous formulation of daratumumab co-formulated with hyaluronidase-fihj is also approved for the treatment of adults with multiple myeloma. … approval was based on results from the Phase 3 PERSEUS study, which demonstrated significant improvement in progression-free survival and higher rates of minimal residual disease (MRD) negativity compared to
Levallorphan
go.drugbank.com/drugs/DB00504ApprovedAn opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties.
Lyme disease vaccine (recombinant OspA)
go.drugbank.com/drugs/DB00045ApprovedWithdrawnLipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.
Avenciguat
go.drugbank.com/drugs/DB18882Investigationalor Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)). … Avenciguat is under investigation in clinical trial NCT05282121 (A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis
Lisuride
go.drugbank.com/drugs/DB00589ApprovedAn ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome