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Displaying results 3211 - 3220 of 10000 in total
  1. Drug

    Levallorphan

    go.drugbank.com/drugs/DB00504
    Approved

    An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. … It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants

  2. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    Cannabidivarin, also known as cannabidivarol or CBDV, is a non-psychoactive cannabinoid found within [DB14009]. … , which is a member of a large family of ion channels that are involved in the onset and progression of several types of epilepsy.

    Synonyms: CBD-V
  3. Drug

    Tofisopam

    go.drugbank.com/drugs/DB08811
    Investigational

    Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  4. Drug

    LErafAON

    go.drugbank.com/drugs/DB04973
    Investigational

    Phase I/II trials commenced in March 2001 and were ongoing as of June 2003.

  5. Drug

    Topiroxostat

    go.drugbank.com/drugs/DB01685
    Investigational

    Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. … Renal complications are major comorbidities that limit the [DB00437] therapy as dose reductions are recommended.

    Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C8 Inhibitors
  6. Drug

    Cyclizine

    go.drugbank.com/drugs/DB01176
    ApprovedWithdrawn

    A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  7. Drug

    19-norandrostenedione

    go.drugbank.com/drugs/DB01434
    ExperimentalIllicit

    After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. … In the body 19-norandrostenedione is rapidly metabolized into [nandrolone], also known as nortestosterone.

  8. Drug

    AR-9281

    go.drugbank.com/drugs/DB06345
    Investigational

    AR-9281 inhibits soluble epoxide hydrolase.

  9. Drug

    Selenomethionine

    go.drugbank.com/drugs/DB11142
    ApprovedInvestigational

    *In vivo*, selenomethionine plays an essential role in acting as an antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of glutathione, another important … Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans.

  10. Drug

    Dyphylline

    go.drugbank.com/drugs/DB00651
    ApprovedWithdrawn

    Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

    Mixtures: ESPEKTAN A ŞURUP, 100 ML