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Displaying results 3231 - 3240 of 10000 in total
  1. Target

    Interleukin-10 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0014391
    TargetHumans

    Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, all...

    Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1
  2. Target

    Bcl-2-like protein 10

    go.drugbank.com/bio_entities/BE0019838
    TargetHumans

    Promotes cell survival by suppressing apoptosis induced by BAX but not BAK (PubMed:11278245, PubMed:11689480). Increases binding of AHCYL1/IRBIT to ITPR1 (PubMed:27995898). Reduces ITPR1-mediated calcium release from the endoplasmic reti...

    Polypeptides: Bcl-2-like protein 10Synonyms: Bcl2-L-10
  3. Target

    START domain-containing protein 10

    go.drugbank.com/bio_entities/BE0021582
    TransporterHumans

    May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl cha...

    Polypeptides: START domain-containing protein 10Synonyms: StAR-related lipid transfer protein 10
  4. Drug

    Levocabastine

    go.drugbank.com/drugs/DB01106
    Approved

    Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.

    Categories: Heterocyclic Compounds, 1-Ring, Decongestants and AntiallergicsProducts: Levocamed 0,5 mg/ml Augentropfensuspension, Levocamed 0,5 mg/ml Nasenspray, Suspension
  5. Target

    5'-nucleotidase

    go.drugbank.com/bio_entities/BE0001096
    TargetEnzymeHumans

    Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:22997138, PubMed:23142347, PubMed:24887587, PubMed:344...

    Polypeptides: 5'-nucleotidaseSynonyms: 5'-NT, 5'-deoxynucleotidase
  6. Target

    Interleukin-5

    go.drugbank.com/bio_entities/BE0001208
    TargetHumans

    Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting ...

    Polypeptides: Interleukin-5Synonyms: IL-5
  7. Target

    Kallikrein-5

    go.drugbank.com/bio_entities/BE0010708
    TargetHumans

    May be involved in desquamation

    Polypeptides: Kallikrein-5
  8. Drug

    Maprotiline

    go.drugbank.com/drugs/DB00934
    Approved

    Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.

    Categories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Cytochrome P-450 SubstratesProducts: MAPROTILIN-NEURAX 50 MG, Ludiomil 50 mg - Filmtabletten
  9. Drug

    Fish oil

    go.drugbank.com/drugs/DB13961
    ApprovedInvestigationalNutraceutical

    However, prescription-only fish oil products are sometimes prescribed for individuals who demonstrate severe (>= 500 mg/dL) hypertriglyceridemia [FDA Label]. … Furthermore, a variety of studies regarding additional potential actions of fish oil omega-3-fatty acids EPA and DHA are ongoing.

    Mixtures: OGAMIX(Evening primrose oil 500 mg, Lecithin oil 500 mg, Fish oil 125 mgand Vitamin E 10 mg Soft Gelatin Capsule), SMOFlipid 200 mg/ml Emulsion zur InfusionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Doxazosin

    go.drugbank.com/drugs/DB00590
    ApprovedInvestigational

    Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. … Other members of this drug class include [Prazosin], [Terazosin], [Tamsulosin], and [Alfuzosin].[A180661] Because of its long-lasting effects, doxazosin can be administered once a day.

    Synonyms: 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin, 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazinInternational brands: Cardura-1, Cardura-2