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Lymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawnLymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. … [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and efficacy.[A203255] Lymecycline was initially discovered in 1961.
Synonyms: N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline, (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamideProducts: TETRALYSAL® CAPSULAS 300 MG, CycloPel 300 mg KapselnProtriptyline
go.drugbank.com/drugs/DB00344ApprovedTCAs also block histamine H<sub>1</sub> receptors, alpha<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … In depressed individuals, protriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: P-glycoprotein inhibitorsSynonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamineLinzagolix
go.drugbank.com/drugs/DB17083ApprovedInvestigationalUterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with heavy menstrual bleeding, anemia, abdominal pain and pressure, bloating, increased urinary frequency … Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor.
Categories: Heterocyclic Compounds, 1-Ring, Pituitary and Hypothalamic Hormones and AnaloguesSynonyms: 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(3,4-d)pyrimidine-5-carboxylic acid, Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-2,4-dioxo-Clorazepic acid
go.drugbank.com/drugs/DB00628ApprovedIllicitSimilar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA) to the GABA type A (GABA-A) receptor, which promotes channel opening and neuronal … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.
Categories: Benzodiazepines and benzodiazepine derivatives, Cytochrome P-450 SubstratesSynonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid5-methyltetrahydrofolic acid
go.drugbank.com/drugs/DB04789InvestigationalNutraceutical5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases
Synonyms: 5-methyltetrahydrofolic acid, 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acidInternational brands: Prefolic AAllantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].
Synonyms: SD-101, 5-UreidohydantoinMixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 GDantrolene
go.drugbank.com/drugs/DB01219ApprovedInvestigationalChemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Categories: Heterocyclic Compounds, 1-Ring, Dantrolene and DerivativesSynonyms: 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin5-Methyluridine triphosphate
go.drugbank.com/drugs/DB04243ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: 5-METHYLURIDINE 5'-TRIPHOSPHATE, URIDINE, 5-METHYL-, 5'-TRIPHOSPHATEP1-(adenosine-5'-P5-(uridine-5')pentaphosphate
go.drugbank.com/drugs/DB03664ExperimentalSynonyms: P1-(adenosine-5'-P5-(uridine-5')pentaphosphate5'-S-[2-(decylamino)ethyl]-5'-thioadenosine
go.drugbank.com/drugs/DB07413ExperimentalSynonyms: 5'-S-[2-(decylamino)ethyl]-5'-thioadenosine