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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
go.drugbank.com/bio_entities/BE0000525TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371). … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371).
Synonyms: Complex I-B16.6Baculoviral IAP repeat-containing protein 3
go.drugbank.com/bio_entities/BE0010674TargetHumansProtects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner.
Synonyms: TNFR2-TRAF-signaling complex protein 1RuvB-like 2
go.drugbank.com/bio_entities/BE0009019TargetHumansMay play a role in regulating the composition of the U5 snRNP complex (PubMed:28561026) … Proposed core component of the chromatin remodeling INO80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (PubMed:16230350, PubMed:21303910
Synonyms: INO80 complex subunit JRetinol dehydrogenase 11
go.drugbank.com/bio_entities/BE0002321TargetHumansRetinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12036956, PubMed:12226107, PubMed:29410696). Exhibits a low redu...
Synonyms: HCV core-binding protein HCBP12General transcription and DNA repair factor IIH helicase/translocase subunit XPB
go.drugbank.com/bio_entities/BE0012820TargetHumansComponent of the general transcription and DNA repair factor IIH (TFIIH) core complex (PubMed:10024882, PubMed:17466626, PubMed:8157004, PubMed:8465201). … The structure of the TFIIH transcription complex differs from the NER-TFIIH complex; large movements by XPD/ERCC2 and XPB/ERCC3 are stabilized by XPA (PubMed:31253769, PubMed:33902107).
Synonyms: TFIIH basal transcription factor complex 89 kDa subunitCyclin-dependent kinases
go.drugbank.com/bio_entities/BE0010231TargetHumansComponent of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex … Phosphorylates SKA3 on multiple sites during mitosis which promotes SKA3 binding to the NDC80 complex and anchoring of the SKA complex to kinetochores, to enable stable attachment of mitotic spindle microtubules
Synonyms: Mediator complex subunit CDK8, Tat-associated kinase complex catalytic subunitNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [L11985] Neomycin sulfate is the most common form for pharmaceutical preparations; because the compound is a complex, the amount of neomycin in products is measured in units.
Mixtures: QUIR®, Tyrothricin "Provita" comp. - LutschtablettenPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxi...
Mixtures: QUIR®Avobenzone
go.drugbank.com/drugs/DB09495ApprovedInvestigationalAvobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as ...
Mixtures: 360 by QUR Spanish lime lip balm, 360 by QUR Vanilla lace lip balmOctisalate
go.drugbank.com/drugs/DB11062ApprovedAlso known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicyla...
Mixtures: 360 by QUR Spanish lime lip balm, 360 by QUR Vanilla lace lip balm