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Displaying results 321 - 330 of 7655 in total
  1. Drug

    Ocrelizumab

    go.drugbank.com/drugs/DB11988
    ApprovedInvestigational

    It was later approved by Health Canada in August 2017, making the drug the first available treatment for PPMS in both the US and Canada. … The addition of hyaluronidase allows for subcutaneous injection, which is a method often preferable for patients and provides an alternative means of administration for sites lacking IV infrastructure,

    Products: OCREVUS 300mg/10mL Concentrate for Solution for Infusion
  2. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used...

    Synonyms: [(o-carboxyphenyl)thio]ethylmercury sodium salt, ethylmercurithiosalicylic acid sodium saltCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Vedolizumab

    go.drugbank.com/drugs/DB09033
    ApprovedInvestigational

    [L48216] Vedolizumab was developed by Takeda and approved by the FDA under the brand name ENTYVIO for the maintenance therapy of moderately to severely active Ulcerative Colitis and Crohn’s Disease … is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative colitis or

    Products: Entyvio 300mg Powder for Concentrate for Solution for Infusion, ENTYVIO POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 300MG/VIAL
  4. Drug

    Deferoxamine

    go.drugbank.com/drugs/DB00746
    ApprovedInvestigational

    It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.

    Categories: Compounds used in a research, industrial, or household settingProducts: Desferal 500mg Powder for Solution for Injection, Deferoxamine Mesylate for Injection
  5. Indication

    At Risk for HIV

    go.drugbank.com/conditions/DBCOND0051697
    Drugs: Emtricitabine · Tenofovir alafenamide · Tenofovir disoproxil
    Synonyms: At Risk for HIV, Risk for HIV Infection
  6. Indication

    Candidate for systemic therapy

    go.drugbank.com/conditions/DBCOND0101669
    Drugs: Abrocitinib · Apremilast · Baricitinib · Bimekizumab · Certolizumab pegol · Dupilumab +9 more
    Synonyms: Candidate for systemic therapy
  7. Drug

    Tirzepatide

    go.drugbank.com/drugs/DB15171
    ApprovedInvestigational

    agonist for this indication. … [L41820] Later, it was approved under a different brand name ZEPBOUND on November 8, 2023, for the chronic weight management in adults with obesity or overweight with at least one weight-related condition

    Products: Mounjaro 5 mg solution for injection in vial, Mounjaro 10 mg solution for injection in vial
  8. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    [A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel].

    Products: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION)
  9. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of

    Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: PRALUENT 150 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN), PRALUENT 75 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN)
  10. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    The sodium salt has been also used to treat primary pulmonary hypertension.

    Products: VELETRI POWDER FOR SOLUTION FOR INFUSION 0.5MG/VIAL, VELETRI POWDER FOR SOLUTION FOR INFUSION 1.5MG/VIAL