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Anethole trithione
go.drugbank.com/drugs/DB13853ApprovedAnethole trithione (ATT) appears to have a broad range of unique functions, from increasing salivary secretion to help treat xerostomia , to demonstrating an ability to inhibit carcinogenesis by increasing the activity of electrophile de...
Demegestone
go.drugbank.com/drugs/DB13857ExperimentalDemegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEtynodiol
go.drugbank.com/drugs/DB13866ExperimentalEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see DB008...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnFluticasone is a synthetic glucocorticoid available as 2 esters, DB08906 and DB00588 [FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications [FDA Label]. DB00588 was ...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPhloxine B
go.drugbank.com/drugs/DB13911ApprovedWithdrawnPhloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsEmicizumab
go.drugbank.com/drugs/DB13923ApprovedInvestigationalEmicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X.
Products: HEMLIBRA 30MG/ML SOLUTION FOR INJECTION, HEMLIBRA 150MG/ML SOLUTION FOR INJECTIONNonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalNonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation...
WIN 55212-2
go.drugbank.com/drugs/DB13950ExperimentalWIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It is a potent cannabino...
Synonyms: (2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors1,2-dichlorobenzene
go.drugbank.com/drugs/DB13963ApprovedWithdrawn1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound by the presence of t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesRacemethionine
go.drugbank.com/drugs/DB13972ApprovedA preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Synonyms: DL-Methionine, DL-Methioninum