Search
Aluminium phosphate
go.drugbank.com/drugs/DB14517ApprovedInvestigationalCategories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsRamelteon
go.drugbank.com/drugs/DB00980ApprovedInvestigationalIt is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse. … Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN).
Categories: Hypnotics and SedativesOzenoxacin
go.drugbank.com/drugs/DB12924Approveds Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age … that has demonstrated safe and effective therapy in both the adult and pediatric population.
Cinchocaine
go.drugbank.com/drugs/DB00527ApprovedVet approvedIt is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Categories: Analgesics and Anesthetics, Antipruritics and Local AnestheticsSynonyms: 2-N-butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-butoxy-N-(2-(diethylamino)ethyl)cinchoninamideLobeglitazone
go.drugbank.com/drugs/DB09198InvestigationalLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. … It primarily functions as an insulin sensitizer by binding and activating Peroxisome Proliferator-Activated Receptors (PPAR) gamma within fat cells.
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismOxitriptan
go.drugbank.com/drugs/DB02959ApprovedInvestigationalNutraceuticalWithdrawnthe United Kingdom, United States and Canada as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, and is also marketed in many European countries for the indication … 5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and metabolic intermediate in the synthesis of serotonin and melatonin. 5-HTP is sold over-the-counter in
Categories: Amino Acids, Peptides, and ProteinsBeremagene geperpavec
go.drugbank.com/drugs/DB17831ApprovedInvestigational[L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component of the anchoring fibrils for dermal–epidermal cohesion. … Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB).
Categories: Cellular and Gene Therapy, Preparations for Treatment of Wounds and UlcersDoxecitine
go.drugbank.com/drugs/DB02594ApprovedInvestigationalIt is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair. … This combination is the first and only approved treatment for Thymidine Kinase 2 deficiency.[L54613, L54618]
Categories: Nucleic Acids, Nucleotides, and NucleosidesPorfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalIt is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. … It is the first drug to be approved in the use of photodynamic therapy in the United States.
Categories: Antineoplastic and Immunomodulating Agents, Sensitizers Used in Photodynamic/radiation TherapyInternational brands: Photofrin IIPegloticase
go.drugbank.com/drugs/DB09208ApprovedInvestigational[L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration of pegloticase and methotrexate.[L42425] … Therefore therapeutic drug levels can be maintained with infrequent and relatively low pegloticase doses.[A249980] The PEG group also gives pegloticase a lower potential to induce an immune response.
Categories: Enzymes and Coenzymes, Compounds used in a research, industrial, or household setting