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Displaying results 3341 - 3350 of 10000 in total
  1. Drug

    Pracinostat

    go.drugbank.com/drugs/DB05223
    Investigational

    Data demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors. … Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing.

    Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Anisotropine methylbromide

    go.drugbank.com/drugs/DB00517
    Approved

    Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. … Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant

    Synonyms: 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide, endo-8,8-Dimethyl-3-((1-oxo-2-propylpentyl)oxy)-8-azoniabicyclo(3.2.1)octane bromide
  3. Drug

    Aceclidine

    go.drugbank.com/drugs/DB13262
    Approved

    [A274273] It has also been studied in the treatment of presbyopia, a common age-related vision loss where the crystalline lens hardens and loses elasticity, impairing near vision. … Aceclidine is a cholinergic muscarinic agonist which began marketing in Europe in the 1970s for the treatment of glaucoma.

    Categories: Cholinergic Receptor AgonistSynonyms: 3-Acetoxyquinuclidine
  4. Drug

    Suramin

    go.drugbank.com/drugs/DB04786
    Investigational

    (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin is manufactured by Bayer in Germany as Germanin®. … A polyanionic compound with an unknown mechanism of action.

  5. Drug

    Omega-3 fatty acids

    go.drugbank.com/drugs/DB11133
    ApprovedInvestigationalNutraceutical

    Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S. … Omega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain.

    Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: Animi-3 with Vitamin D, aspen nutrition Omega 3-6-9
  6. Drug

    Caffeine

    go.drugbank.com/drugs/DB00201
    ApprovedInvestigational

    This correlates to about 1 in 10 births. … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.

    Mixtures: Green Guard Pain and Ache Relief, Green Guard Extra Strength Pain ReliefCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  7. Target

    Maltoporin

    go.drugbank.com/bio_entities/BE0003212
    TargetTransporterEscherichia coli (strain K12)

    Also acts as a receptor for several bacteriophages including lambda (PubMed:4201774). Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility (PubMed:2832377).

    Synonyms: Lambda receptor protein, Phage lambda receptor protein
  8. Drug

    Conatumumab

    go.drugbank.com/drugs/DB11646
    Investigational

    Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.

  9. Drug

    Epacadostat

    go.drugbank.com/drugs/DB11717
    Investigational

    Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.

  10. Drug

    Emicerfont

    go.drugbank.com/drugs/DB12910
    Investigational

    Emicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and Irritable Bowel Syndrome (IBS).

    Categories: Heterocyclic Compounds, 1-Ring