Epacadostat

DB11717InvestigationalSmall molecule

Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others.

Mechanism: Pharmacologically active on Indoleamine 2,3-dioxygenase 1
Curator reviewed
Formula / weight: C₁₁H₁₃BrFN₇O₄S · 438.23 g/mol (avg)
Code names: INCB-024360

Resolves to

Compound

Clinical / RWD

Structure

InChIKeyFBKMWOJEPMPVTQ-UHFFFAOYSA-NSMILESNS(=O)(=O)NCCNC1=NON=C1\C(NC1=CC=C(F)C(Br)=C1)=N\O

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

39Drug interactionsStructured to mechanism, not free text

57Clinical trialsPhase, status and sponsor resolved per trial

1ATC codeIncluding every combination product, plus 7 drug categories

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Epacadostat, and which of those have an active Phase 3 trial?

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