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Tianeptine
go.drugbank.com/drugs/DB09289InvestigationalTianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) [A31983]. … Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: STABLON TABLET 12.5 mg, STABLON 12.5 MG TABLET, 60 ADETPolydextrose
go.drugbank.com/drugs/DB14836ExperimentalPolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
Categories: Compounds used in a research, industrial, or household settingPalifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalPalifermin was granted FDA approval on 15 December 2004.[L17933]
Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigational[A232955] Other types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and [avalglucosidase alfa]. … ,[L45275] and the EMA fully approved the drug on March 27, 2023.
Synonyms: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphateGuanidine
go.drugbank.com/drugs/DB00536ApprovedIt is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. … (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
CYT-6091
go.drugbank.com/drugs/DB05991ExperimentalCYT-6091 (Aurimune) is an investigational small molecule made up of recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol bound to the surface of 27 nm colloidal gold … It was under investagtion in clinical trials NCT00356980 and NCT00436410 for the treatment of various cancers.
Categories: Compounds used in a research, industrial, or household settingPirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigational[A251365] The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat IPF.[A251165] … [A251370] While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and modulate cellular oxidation.
Products: PIRFENIDONE EG, ESBRIET HARD CAPSULE 267 MGSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalpermeability of the blood-brain barrier, which allows for the passage of pro-inflammatory mediators into the CNS. … [L15536] Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central nervous system (CNS) involving demyelinating lesions
Products: ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe, ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETPropylhexedrine
go.drugbank.com/drugs/DB06714ApprovedIt is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.
Diiodohydroxyquinoline
go.drugbank.com/drugs/DB09115ApprovedDiiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown.