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Gallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigational[A17097] GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness. … [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone.
Tolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnTolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. … It is used in treatment of persistent pulmonary hypertension of the newborn.
Categories: Adrenergic alpha-1 Receptor AntagonistsFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICACategories: Corticosteroid Hormone Receptor AgonistsEthylenediamine
go.drugbank.com/drugs/DB14189ApprovedSensitivity to ethylenediamine may be identified with a clinical patch test. … Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Forasartan
go.drugbank.com/drugs/DB01342ExperimentalForasartan competes with angiotensin II for binding at the AT1 receptor subtype. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.
Categories: Agents Acting on the Renin-Angiotensin System, Angiotensin Receptor AntagonistsAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigationalfragment C5a and its cognate C5aR receptor in AAV. … presence of ANCAs in the serum.
Categories: Complement 5a Receptor AntagonistTeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalIt is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Eugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalIts exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction. … There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache.
Amisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalIn the US, the intravenous formulation of amisulpride is used to treat and prevent postoperative nausea and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of … [L32759] It is marketed under the brand name Barhemsys.
Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor AntagonistsPancrelipase amylase
go.drugbank.com/drugs/DB11065ApprovedInvestigational[L2509] The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch into more available saccharide forms. … [T177] The pancrelipase amylase is a single polypeptide chain containing two SH groups and four disulfide bridges.