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Frangula purshiana bark
go.drugbank.com/drugs/DB15478ApprovedMixtures: Le 100 B, Herbalax Forte No 70 TabME-344
go.drugbank.com/drugs/DB13062InvestigationalME-344 has been used in trials studying the treatment of Solid Tumors.
Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnIn biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone, 1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-oneUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawn[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138] … Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.
Synonyms: Two-chain urokinaseProducts: UROCHINASI EGMGD-024
go.drugbank.com/drugs/DB17265InvestigationalMGD-024 is an anti-CD123/anti-CD3 bispecific DART molecule.
Suplatast
go.drugbank.com/drugs/DB19138InvestigationalSuplatast is under investigation in clinical trial NCT05983471 (Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)).
Kisspeptin-10
go.drugbank.com/drugs/DB16210InvestigationalKisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).
Synonyms: Kisspeptin-10, Kisspeptin-10 (human)AG-858
go.drugbank.com/drugs/DB05502InvestigationalAG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. … Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models.
LG-100268
go.drugbank.com/drugs/DB01941ExperimentalLG-100268 is a retinoid X receptor (RXR) selective compound.