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Displaying results 3381 - 3390 of 10000 in total
  1. Target

    Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

    go.drugbank.com/bio_entities/BE0008997
    TargetHumans

    May be involved in the interferon response pathway … Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts.

    Polypeptides: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1Synonyms: Cap methyltransferase 1
  2. Target

    Serine/threonine-protein kinase Nek9

    go.drugbank.com/bio_entities/BE0009500
    TargetHumans

    Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817). … Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues (PubMed:11864968).

    Synonyms: Never in mitosis A-related kinase 9
  3. Drug

    Plecanatide

    go.drugbank.com/drugs/DB13170
    ApprovedInvestigational

    It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).

    Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and Proteins
  4. Drug

    Gadoteridol

    go.drugbank.com/drugs/DB00597
    ApprovedInvestigational

    [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876] … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    [A32512] It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. … [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium and chloride.[L2261]

    Categories: Amino Acids, Peptides, and Proteins
  6. Indication

    Coronary artery thrombosis

    go.drugbank.com/conditions/DBCOND0007525
    Drugs: Atorvastatin
    Synonyms: Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
  7. Indication

    Diabetic Retinopathy (DR)

    go.drugbank.com/conditions/DBCOND0118126
    Drugs: Aflibercept · Ranibizumab
    Synonyms: Retinopathy co-occurrent and due to diabetes mellitus
  8. Indication

    Ophthalmia Neonatorum

    go.drugbank.com/conditions/DBCOND0000276
    Drugs: Erythromycin
    Synonyms: Neonatal conjunctivitis and dacryocystitis
  9. Indication

    Undescended Testis

    go.drugbank.com/conditions/DBCOND0033671
    Drugs: Chorionic Gonadotropin (Human)
    Synonyms: Undescended and ectopic testicle
  10. Drug

    Estradiol cypionate

    go.drugbank.com/drugs/DB13954
    ApprovedVet approved

    in potency and in estrogenic effects. … First-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102].

    Mixtures: OBAT SUNTIK KB IICategories: Hormones, Hormone Substitutes, and Hormone Antagonists