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Riluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: RILUTEK® TABLETAS X 50MG, TEGLUTIK® SUSPENSIÓN ORAL 5 MG/MLScopolamine
go.drugbank.com/drugs/DB00747ApprovedInvestigational[A228758, L31578] Due to its dose-dependent adverse effects, scopolamine was the first drug to be offered commercially as a transdermal delivery system, Scopoderm TTS®, in 1981. … [A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently available as both oral tablets and a transdermal delivery system.[L31578]
Mixtures: B-DonnaCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: LİDORİN %5+%5 KREM, 1 ADET 5 G, LİDORİN %5+%5 KREM, 5 ADET 5 GSynonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, 2-(Propylamino)-o-propionotoluidideEpinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic
Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADACategories: Cytochrome P-450 Substrates, P-glycoprotein substratesTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalTranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. … A propylamine formed from the cyclization of the side chain of amphetamine.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineIsoflurane
go.drugbank.com/drugs/DB00753ApprovedInvestigationalVet approvedA stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 1-chloro-2,2,2-trifluoroethyl difluoromethyl etherClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalClopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.
Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Mixtures: Super C-M-K, Potassium Chloride 0.15% w/v and Glucose 5% w/v Intravenous Infusion BPInternational brands: Slow-K, Micro-KClavulanic acid
go.drugbank.com/drugs/DB00766ApprovedInvestigationalVet approvedClavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin] to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening
Mixtures: SUMIVULIN ® 1.2 G (1 G / 0.2 G), IPICLAV® 1 GCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBenzquinamide
go.drugbank.com/drugs/DB00767ApprovedWithdrawnBenzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring