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Displaying results 331 - 340 of 3387 in total
  1. Target

    Glucocorticoid receptor

    go.drugbank.com/bio_entities/BE0000794
    TargetHumans

    Receptor for glucocorticoids (GC) (PubMed:27120390, PubMed:37478846).

    Polypeptides: Glucocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 1
  2. Target

    Ferripyoverdine receptor

    go.drugbank.com/bio_entities/BE0001305
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Receptor for the siderophore ferripyoverdine.

    Polypeptides: Ferripyoverdine receptorSynonyms: Ferripyoverdine receptor precursor
  3. Target

    Leptin receptor

    go.drugbank.com/bio_entities/BE0003376
    TargetHumans

    Receptor for hormone LEP/leptin (Probable) (PubMed:22405007).

    Polypeptides: Leptin receptorSynonyms: OB receptor
  4. Target

    Motilin receptor

    go.drugbank.com/bio_entities/BE0003521
    TargetHumans

    Receptor for motilin

    Polypeptides: Motilin receptorSynonyms: G protein-coupled receptor 38
  5. Target

    Transferrin receptor

    go.drugbank.com/bio_entities/BE0004850
    TransporterTargetHumans

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062). … The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.

    Polypeptides: Transferrin receptor protein 1, Transferrin receptor protein 2Synonyms: Transferrin receptor 1
  6. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247)

    Polypeptides: Dopamine receptor D1, Dopamine receptor D2Synonyms: Dopamine D1 receptor, Dopamine D2 receptor
  7. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC
  8. Drug

    Trolamine

    go.drugbank.com/drugs/DB13747
    ApprovedInvestigational

    It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin and hair conditioning products.

  9. Target

    Androgen receptor

    go.drugbank.com/bio_entities/BE0000132
    TargetHumans

    activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor

    Polypeptides: Androgen receptorSynonyms: Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
  10. Target

    Calcitonin receptor

    go.drugbank.com/bio_entities/BE0000431
    TargetHumans

    CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively (PubMed:35324283, PubMed:38603770). … IAPP, CT and CGRP1 activate CALCR and AMYRs with distinct modes of receptor activation resulting in specific phenotypes (PubMed:35324283, PubMed:38603770).

    Polypeptides: Calcitonin receptorFunction: amylin receptor activity