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Displaying results 331 - 340 of 10000 in total
  1. Drug

    Protriptyline

    go.drugbank.com/drugs/DB00344
    Approved

    TCAs also block histamine H<sub>1</sub> receptors, alpha<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … See toxicity section below for a complete listing of side effects. Protriptyline may be used for the treatment of depression.

    Categories: P-glycoprotein inhibitorsSynonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine
  2. Drug

    Linzagolix

    go.drugbank.com/drugs/DB17083
    ApprovedInvestigational

    Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. … It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.

    Synonyms: 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(3,4-d)pyrimidine-5-carboxylic acid, Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-1,2,3,4-tetrahydro-2,4-dioxo-Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  3. Drug

    Lymecycline

    go.drugbank.com/drugs/DB00256
    ApprovedInvestigationalWithdrawn

    [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and efficacy.[A203255] Lymecycline was initially discovered in 1961. … It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries.

    Synonyms: N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline, (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamideProducts: TETRALYSAL® CAPSULAS 300 MG, CycloPel 300 mg Kapseln
  4. Drug

    Lormetazepam

    go.drugbank.com/drugs/DB13872
    Approved

    It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
  5. Drug

    5-methyltetrahydrofolic acid

    go.drugbank.com/drugs/DB04789
    InvestigationalNutraceutical

    5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases

    Synonyms: 5-methyltetrahydrofolic acid, 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acidInternational brands: Prefolic A
  6. Drug

    Cannabidiol

    go.drugbank.com/drugs/DB09061
    ApprovedInvestigational

    These effects are largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 (CB1 and CB2)[A32585,A32824]. … It is approved for use as adjunctive treatment for symptomatic relief of spasticity in adult patients with multiple sclerosis (MS).

    Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsSynonyms: (1'R,2'R)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydrobiphenyl-2,6-diol, (−)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol
  7. Drug

    Ioversol

    go.drugbank.com/drugs/DB09134
    ApprovedInvestigational

    [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.

    Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedSynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide
  8. Drug

    P1-(adenosine-5'-P5-(uridine-5')pentaphosphate

    go.drugbank.com/drugs/DB03664
    Experimental

    Synonyms: P1-(adenosine-5'-P5-(uridine-5')pentaphosphate
  9. Drug

    5'-S-[2-(decylamino)ethyl]-5'-thioadenosine

    go.drugbank.com/drugs/DB07413
    Experimental

    Synonyms: 5'-S-[2-(decylamino)ethyl]-5'-thioadenosine
  10. Drug

    5-Methyluridine triphosphate

    go.drugbank.com/drugs/DB04243
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-METHYLURIDINE 5'-TRIPHOSPHATE, URIDINE, 5-METHYL-, 5'-TRIPHOSPHATE