Search
Tianeptine
go.drugbank.com/drugs/DB09289InvestigationalTianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) [A31983]. … Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; it is also marketed in several other European countries under the trade name “Coaxil” as well as in
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexDifamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigational[L55042, A275424, A275420] As difamilast's mechanism of action involves the inhibition of PDE4, the inhibition leads to an increase in intracellular cyclic AMP and a subsequent decrease in the production … [A275420] Difamilast is a selective PDE4 inhibitor and the inhibition of phosphodiesterase-4 (PDE4) reduces proinflammatory mediators and cytokines in atopic dermatitis.
GI-4000
go.drugbank.com/drugs/DB05698InvestigationalA vaccine containing a heat-killed recombinant <em>Saccharomyces cerevisiae</em> yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant
Carbimazole
go.drugbank.com/drugs/DB00389ApprovedAn imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Products: CARBIMAZOL 1A PHARMA 5MG, CARBIMAZOL 1A PHARMA 10MGChlormezanone
go.drugbank.com/drugs/DB01178ApprovedWithdrawnA non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Synonyms: 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxideQuercetin
go.drugbank.com/drugs/DB04216InvestigationalQuercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Categories: Compounds used in a research, industrial, or household settingAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. … Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%.
Synonyms: n-nonanedioic acidOlaflur
go.drugbank.com/drugs/DB13290InvestigationalOlaflur which is also referred to as elmex gel is an ingredient used in toothpaste which helps in the prevention of dental caries.
Categories: Compounds used in a research, industrial, or household settingChikungunya vaccine (live, attenuated)
go.drugbank.com/drugs/DB18701ApprovedInvestigationalChikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952.[A262051] It is spread primarily by the bite of infected mosquitos of the _Aedes_ genus. … [A262051] Prior to 2013, chikungunya virus cases and outbreaks had been identified in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans.
Categories: Complex MixturesOlaratumab
go.drugbank.com/drugs/DB06043ApprovedInvestigationalStudies show that the treatment of olaratumab in combination with doxorubicin resulted in significant reduction of cancer cell proliferation and tumor growth. … Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-α with high affinity