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Displaying results 3401 - 3410 of 10000 in total
  1. Drug

    Fenfluramine

    go.drugbank.com/drugs/DB00574
    ApprovedIllicitInvestigationalWithdrawn

    Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life following exposure to elevated temperatures. … [A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as an appetite suppressant until concerns regarding cardiotoxicity in obese patients lead to its withdrawal

    Synonyms: 1-(m-trifluoromethyl-phenyl)-2-ethylaminopropaneInternational brands: Ponderax PA
  2. Drug

    Sonlicromanol

    go.drugbank.com/drugs/DB16333
    Investigational

    Sonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).

    Synonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideCategories: Vitamin E, analogs & derivatives, Compounds used in a research, industrial, or household setting
  3. Drug

    Bromodiphenhydramine

    go.drugbank.com/drugs/DB01237
    Approved

    Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.

    Synonyms: 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine, β-(p-bromobenzhydryloxy)ethyldimethylamine
  4. Drug

    Sulprostone

    go.drugbank.com/drugs/DB12708
    Investigational

    Sulprostone has been used in trials studying Abortion, Induced.

    Categories: Prostaglandins E
  5. Drug

    Alimemazine

    go.drugbank.com/drugs/DB01246
    ApprovedVet approvedWithdrawn

    A phenothiazine derivative that is used as an antipruritic.

    Categories: Heterocyclic Compounds, 3-Ring
  6. Drug

    Troglitazone

    go.drugbank.com/drugs/DB00197
    ApprovedWithdrawn

    Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  7. Drug

    Pimavanserin

    go.drugbank.com/drugs/DB05316
    ApprovedInvestigational

    [L48236] Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5-HT<sub>2A</sub> and HT<sub>2C</sub> receptors. … [L48241,A232573] Pimavanserin was also under review as a potential treatment for dementia-related psychosis; however, as of April 2021, FDA approval has not been granted for this indication despite previous

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  8. Drug

    Hydroquinidine

    go.drugbank.com/drugs/DB15300
    Investigational

    Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).

    Categories: Antiarrhythmics, Class Ia, Antiarrhythmics, Class I
  9. Drug

    Lorajmine

    go.drugbank.com/drugs/DB13651
    Experimental

    Categories: Antiarrhythmics, Class Ia, Antiarrhythmics, Class I
  10. Drug

    gamma-Tocopherol

    go.drugbank.com/drugs/DB15394
    Experimental

    gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).

    Synonyms: D-gamma-TocopherolCategories: Vitamin E, Compounds used in a research, industrial, or household setting