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Meclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigationalMeclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. … [L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets.
Products: Trav-L-tabs, Dramamine - NR1295
go.drugbank.com/drugs/DB05122ExperimentalR1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis. … Integrins are associated to the pathology seen in some of the autoimmune diseases such as rheumatoid arthritis.
Dextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnThe levo-isomer appears to exhibit a very limited antitussive effect. … Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions.
Mixtures: Darvocet-N 50, Darvocet-N 100Products: Darvon-NTiaprofenic acid
go.drugbank.com/drugs/DB01600ApprovedTiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain.
Products: Penta-tiaprofenic TabletsAxitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigational[L6676] Axitinib is an indazole derivative.[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideDibekacin
go.drugbank.com/drugs/DB13270ApprovedDibekacin is an aminoglycoside antibiotic marketed in Japan [L5623].
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexCatridecacog
go.drugbank.com/drugs/DB09310ApprovedCoagulation Factor XIII A-Subunit (Recombinant) is available in the US as the commmercially available product Tretten, and in the EU as NovoThirteen. … Compared to Coagulation Factor XIII A-Subunit (Recombinant), which is produced through recombinant DNA technology where the target protein is grown in yeast and then isolated, the human form is isolated
Synonyms: Factor XIII A-Subunit (Recombinant), Coagulation Factor XIII A-Subunit (recombinant)Risdiplam
go.drugbank.com/drugs/DB15305ApprovedInvestigationalRisdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). … [L15351,A216871] Risdiplam was approved by the FDA in August 2020 for the treatment of spinal muscular atrophy (SMA).
Azelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. … Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%.
Synonyms: n-nonanedioic acidEbola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigational[L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing. … Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by _Zaire ebolavirus_ in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks.
Synonyms: Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP