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Bisegliptin
go.drugbank.com/drugs/DB06127InvestigationalIt is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion … Bisegliptin is a compound for the treatment of type 2 diabetes.
Categories: DPP-IV InhibitorsEdotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494ApprovedEdotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). … [L8597] [Dotatate gallium Ga-68] is used for a similar indication.[A185852] Dotatate gallium Ga-68 has lower tumor uptake but this data is highly variable between patients.
Hydroxyamphetamine
go.drugbank.com/drugs/DB09352Approvedstinging in the eyes. … Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and temporary
Pizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedToluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Categories: Compounds used in a research, industrial, or household settingFerumoxsil
go.drugbank.com/drugs/DB09507ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingAcetylcholine
go.drugbank.com/drugs/DB03128ApprovedInvestigationalIt is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications. … Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in
Isoeugenol
go.drugbank.com/drugs/DB14188ApprovedIsoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. … It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry [A34278].
Synonyms: 2-methoxy-4-(prop-1-en-1-yl)phenolImetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigationalImetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase. … [A187838] Imetelstat received FDA approval in June 2024 for use in certain patients with MDS who have transfusion-dependent anemia and are unable to use ESAs.[L50883,L50888]
Colfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawnColfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. … [A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.