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Clidinium
go.drugbank.com/drugs/DB00771ApprovedClidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Synonyms: N-methyl quinuclidinyl benzilateRunt-related transcription factor 1
go.drugbank.com/bio_entities/BE0010423TargetHumansForms the heterodimeric complex core-binding factor (CBF) with CBFB. … RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their
Synonyms: Core-binding factor subunit alpha-2, SL3/AKV core-binding factor alpha B subunitPrednicarbate
go.drugbank.com/drugs/DB01130ApprovedIt is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness.
International brands: Dermatop E EmollientEdotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494Approved[A185852] Edotreotide gallium Ga-68 was granted FDA approval on 21 August 2019.[L8597] … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).
AGRO100
go.drugbank.com/drugs/DB04998InvestigationalSuch binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell. … AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells.
Pemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnPemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. … As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis.
Protein S100-A8
go.drugbank.com/bio_entities/BE0008955TargetHumansActivates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme … The iNOS-S100A8/A9 transnitrosylase complex directs selective inflammatory stimulus-dependent S-nitrosylation of GAPDH and probably multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL
Synonyms: Leukocyte L1 complex light chainIotroxic acid
go.drugbank.com/drugs/DB08945ApprovedWithdrawnIotroxic acid is a contrast medium molecule.
Categories: Compounds used in a research, industrial, or household settingAtrazine
go.drugbank.com/drugs/DB07392Experimental(From The Merck Index, 11th ed) … Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans.
Categories: Compounds used in a research, industrial, or household settingPentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalThe drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.