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Invasive Infection caused by Streptococcus pneumoniae serotype 5
go.drugbank.com/conditions/DBCOND0093623Drugs: Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigenSynonyms: Invasive Infection caused by Streptococcus pneumoniae serotype 5Quinidine barbiturate
go.drugbank.com/drugs/DB01346ApprovedA papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909) … The administration of quinidine derivatives helps to observe various skin and mucosal reactions.
Products: NATISEDINE 100 MG TABLET, 20 ADETAlpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigationalAlpelisib was designed to target this enzyme that appears to be mutated at a rate of nearly 30% in human cancers, leading to hyperactivation. … , differentiation, and metabolism.
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: PİMREVA 200 MG FİLM KAPLI TABLET, 14 ADET, PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADETLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigational[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: LETROL 2.5 MG FILM TABLET, 30 ADET, LETROKABI 2.5 MG FILM TABLET, 30 ADETTryptophan 5-hydroxylase 1
go.drugbank.com/bio_entities/BE0000121TargetEnzymeHumansOxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis
Polypeptides: Tryptophan 5-hydroxylase 1Synonyms: Tryptophan 5-monooxygenase 1Cytosolic purine 5'-nucleotidase
go.drugbank.com/bio_entities/BE0000261TargetEnzymeHumansBroad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705).
Polypeptides: Cytosolic purine 5'-nucleotidaseSynonyms: High Km 5'-nucleotidase, Cytosolic 5'-nucleotidase II5'(3')-deoxyribonucleotidase, mitochondrial
go.drugbank.com/bio_entities/BE0001515TargetHumansDephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).
Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: Deoxy-5'-nucleotidase 2, 5',3'-nucleotidase, mitochondrial5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
go.drugbank.com/bio_entities/BE0001620TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
Polypeptides: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseFunction: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activityOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001677TargetEnzymeEscherichia coli (strain K12)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001956TargetBacillus subtilis (strain 168)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activity