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Displaying results 3451 - 3460 of 10000 in total
  1. Drug

    Gestodene

    go.drugbank.com/drugs/DB06730
    Investigational

    Gestodene is a progestogen hormonal contraceptive.

    Mixtures: Lenea 20 µg/75 µg überzogene Tabletten, FEMIANE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Quaternium-15

    go.drugbank.com/drugs/DB14198
    Approved

    Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. … It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin.

    Synonyms: N-(3-Chloroallyl)hexaminium chloride, 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propen-1-yl)-, chloride (1:1)
  3. Drug

    Vismodegib

    go.drugbank.com/drugs/DB08828
    ApprovedInvestigational

    [A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. … Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)-
  4. Drug

    Mafenide

    go.drugbank.com/drugs/DB06795
    ApprovedVet approvedWithdrawn

    Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. … In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements

    Synonyms: 4-Homosufanilamide, 4-(aminomethyl)benzenesulfonamide
  5. Drug

    Insulin beef

    go.drugbank.com/drugs/DB09456
    Approved

    Insulin beef has been discontinued in the US and Canada since 2017.[L10827]

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 Inducers
  6. Drug

    Forasartan

    go.drugbank.com/drugs/DB01342
    Experimental

    As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. … Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension.

    Categories: Angiotensin II Type 1 Receptor Blockers, Heterocyclic Compounds, 1-Ring
  7. Drug

    Karaya gum

    go.drugbank.com/drugs/DB10535
    Approved

    Karaya gum allergenic extract is used in allergenic testing.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Chlorquinaldol

    go.drugbank.com/drugs/DB13306
    Approved

    [F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. … Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of bacterial vaginosis.[F4552]

    Mixtures: IMPETEX %0.1 + %1 KREM, 10 G, NERISONA-C %0,1 + %1 KREM, 10 GRCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Pyruvic acid

    go.drugbank.com/drugs/DB00119
    ApprovedInvestigationalNutraceutical

    (From Stedman, 26th ed) … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures.

    Synonyms: 2-Oxopropansäure, 2-Oxopropionsäure
  10. Drug

    Indocyanine green

    go.drugbank.com/drugs/DB16024
    ApprovedInvestigationalWithdrawn

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring