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Displaying results 3461 - 3470 of 10000 in total
  1. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase

    go.drugbank.com/bio_entities/BE0003348
    TargetPlasmodium falciparum (isolate 3D7)

    Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseSynonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
  2. Target

    Nuclear receptor coactivator 5

    go.drugbank.com/bio_entities/BE0004057
    TargetHumans

    Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the or...

    Polypeptides: Nuclear receptor coactivator 5Synonyms: NCoA-5
  3. Target

    Interferon-inducible GTPase 5

    go.drugbank.com/bio_entities/BE0004634
    TargetHumans

    GTPase required for sperm motility and therefore male fertility, via positive regulation of spermatozoa fibrous sheath formation

    Polypeptides: Interferon-inducible GTPase 5
  4. Target

    Pyridoxine 5'-phosphate phosphatase

    go.drugbank.com/bio_entities/BE0004713
    EnzymeEnsifer meliloti

    Polypeptides: Pyridoxine 5'-phosphate phosphatase
  5. Target

    Inosine-5'-monophosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0004941
    TargetHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays … Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 1, Inosine-5'-monophosphate dehydrogenase 2Synonyms: Inosine-5'-monophosphate dehydrogenase type II
  6. Target

    5-hydroxytryptamine receptor 3B

    go.drugbank.com/bio_entities/BE0009583
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3BSynonyms: 5-HT3B, 5-HT3-B
  7. Target

    5-hydroxytryptamine receptor 3E

    go.drugbank.com/bio_entities/BE0009586
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3ESynonyms: 5-HT3E, 5-HT3-E
  8. Target

    Toll-like receptor 5

    go.drugbank.com/bio_entities/BE0011820
    TargetHumans

    Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781). Recognizes small molecular motifs named pathogen-associat...

    Polypeptides: Toll-like receptor 5
  9. Target

    Flavin-containing monooxygenase 5

    go.drugbank.com/bio_entities/BE0013329
    EnzymeHumans

    Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters (PubMed:20947616, PubMed:26771671, PubMe...

    Polypeptides: Flavin-containing monooxygenase 5Synonyms: FMO 5, Dimethylaniline oxidase 5
  10. Target

    Pyridoxine-5'-phosphate oxidase

    go.drugbank.com/bio_entities/BE0000181
    TargetEnzymeHumans

    Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

    Polypeptides: Pyridoxine-5'-phosphate oxidase