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5-hydroxytryptamine receptor 5A
go.drugbank.com/bio_entities/BE0004688TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35610220, PubMed:35835867, PubMed:9865521).
Polypeptides: 5-hydroxytryptamine receptor 5ASynonyms: 5-HT-5, 5-HT5A5-hydroxytryptamine 2 receptor
go.drugbank.com/bio_entities/BE0004881TargetHumansPlays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).
Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2A5-hydroxytryptamine receptor 2C
go.drugbank.com/bio_entities/BE0004882TargetRatG-protein coupled receptor for 5-hydroxytryptamine (serotonin).
Polypeptides: 5-hydroxytryptamine receptor 2CSynonyms: 5-HT1C, 5-HT-1C5-hydroxytryptamine receptor 2
go.drugbank.com/bio_entities/BE0004957TargetHumansPlays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:12970106, PubMed:18703043, PubMed:19057895, PubMed:29398112, PubMed:7895773).
Polypeptides: 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2BSynonyms: 5-HT-2, 5-HT-2AChromobox protein homolog 5
go.drugbank.com/bio_entities/BE0009056TargetHumansComponent of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression (PubMed:40440427). In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phospho...
Polypeptides: Chromobox protein homolog 5Serine repeat antigen 5
go.drugbank.com/bio_entities/BE0009196TargetPlasmodium falciparumPolypeptides: Serine repeat antigen 55-hydroxytryptamine receptor 3D
go.drugbank.com/bio_entities/BE0009585TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-DFenofibric acid
go.drugbank.com/drugs/DB13873ApprovedInvestigationalFenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. … for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration.
Mixtures: FENOVAS®10 MG, FENOVAS®10 MGProducts: NORMOLIP NF 45 MG CAPSULAS, TRILIPIX 135 MGCariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigational[A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT<sub>1A</sub> receptors and as an antagonist at serotonin 5-HT<sub>2A</sub> receptors. … Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsSynonyms: trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochlorideBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 SubstratesSynonyms: 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid, p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid