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Displaying results 341 - 350 of 7555 in total
  1. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids.

    Mixtures: Thomas Formula No 17, Thomas Formula No 47Products: Not Applicable, Rea Lo 39
  2. Target

    Flavohemoprotein

    go.drugbank.com/bio_entities/BE0001704
    TargetCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

    Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various

    Synonyms: NO oxygenase
  3. Indication

    Glioblastomas

    go.drugbank.com/conditions/DBCOND0043840
    Drugs: Carmustine · Irinotecan · Temozolomide
    Synonyms: Glioblastoma, no ICD-O subtype, Glioblastoma, no International Classification of Diseases for Oncology subtype
  4. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban was approved by the FDA on December 28, 2012[L6043].

    Products: Nb-apixaban, Nb-apixaban Tablet
  5. Target

    Flavohemoprotein

    go.drugbank.com/bio_entities/BE0002917
    TargetEscherichia coli (strain K12)

    Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various

    Synonyms: NO oxygenase
  6. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    [L5744] In order to function within the body, folic acid must first be reduced by the enzyme dihydrofolate reductase (DHFR) into the cofactors dihydrofolate (DHF) and tetrahydrofolate (THF). … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent

    Mixtures: Super Daily No 2, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHASynonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
  7. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    Its actions are similar to nitroglycerin but with a slower onset of action.

    Products: Nu-isdn Tablets
  8. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178948] The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults.

    Products: NOR TENZ
  9. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.

    Mixtures: ADDAMEL N, Ni-C-E-LE PlusProducts: Rolderme No1
  10. Drug

    Deferasirox

    go.drugbank.com/drugs/DB01609
    ApprovedInvestigational

    Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.

    Products: FUARTE NEO 90 MG FİLM KAPLI TABLET, 30 ADET, FUARTE NEO 180 MG FİLM KAPLI TABLET, 30 ADET