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Pulmonary arterial hypertension WHO functional class I
go.drugbank.com/conditions/DBCOND0160108Synonyms: PAH WHO Group I, Pulmonary Arterial Hypertension WHO Group IRelapsed Cutaneous T-cell Lymphoma Stage I
go.drugbank.com/conditions/DBCOND0168685Drugs: Denileukin diftitoxSynonyms: Relapsed Cutaneous T-cell Lymphoma Stage IMacrophage scavenger receptor types I and II
go.drugbank.com/bio_entities/BE0010942TargetHumansMembrane receptor that mediates the binding, endocytosis and phagocytosis of a broad range of ligands. Recognizes and internalizes modified forms of low-density lipoproteins including acetylated LDL (AcLDL) and oxidized LDL (OxLDL), ther...
Polypeptides: Macrophage scavenger receptor types I and IISynonyms: Macrophage acetylated LDL receptor I and IIAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalAdalimumab-atto was the first adalimumab biosimilar approved by the FDA in 2016.[L44953] Adalimumab-adaz was approved by the FDA on October 31, 2018. … A high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases.
Categories: Miscellaneous GI DrugsProducts: HUMIRA 40MG ILO I E FER, AMGEVITA 40MG ILO I E FERFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigationalFenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. … [L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Mixtures: SIMITRI®145/20MG, PRAVAFEN® CAPSULASCategories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia, P-glycoprotein inhibitorsAmpicillin
go.drugbank.com/drugs/DB00415ApprovedInvestigationalVet approvedAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Mixtures: Ampicillin/Sulbactam Astro 3 g Pulver zur Herstellung einer Injektions- oder Infusionslösung, Ampicillin/Sulbactam Astro 1,5 g Pulver zur Herstellung einer Injektions- oder InfusionslösungCategories: Penicillin G, Heterocyclic Compounds, 2-RingAmmonium chloride
go.drugbank.com/drugs/DB06767ApprovedInvestigationalVet approvedAmmonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Mixtures: NO- TOC JARABE, I-22 SYRUPProducts: Yep wake the faith up Ammonia inhalantFrangula purshiana bark
go.drugbank.com/drugs/DB15478ApprovedMixtures: Herbalax Forte No 70 Tab, Cholasyn IIProducts: Herbalis Cap 80.5mg, Cascara Sagrada Cap 400mgMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidClorazepic acid
go.drugbank.com/drugs/DB00628ApprovedIllicit[A957,L44788] Following administration, clorazepate is rapidly converted to nordiazepam (N-desmethyldiazepam), its active metabolite, before entering systemic circulation. … In September 2020, a black box warning describing these risks was included on the product label of benzodiazepines as per FDA regulation.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid