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  1. Drug

    Chloramphenicol succinate

    go.drugbank.com/drugs/DB07565
    Approved

    Chloramphenicol succinate is an ester prodrug of [chloramphenicol].[A192987] Chloramphenicol is a bacteriostatic antibiotic. … [L14174] Chloramphenicol succinate was granted FDA approval on 20 February 1959.[L12711]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index
  2. Drug

    Bethanechol

    go.drugbank.com/drugs/DB01019
    Approved

    Bethanechol is a synthetic ester that was initially synthesized in 1935. … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous

    Synonyms: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium
  3. Drug

    Glisoxepide

    go.drugbank.com/drugs/DB01289
    Investigational

    However it inhibits taurocholate uptake only in the absence of sodium ions.

    Categories: Drugs Used in Diabetes
  4. Drug

    C326

    go.drugbank.com/drugs/DB06017
    Experimental

    The drug is composed of an IL-6–binding trimer and a IgG-binding domain. … C326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment

  5. Drug

    Asimadoline

    go.drugbank.com/drugs/DB05104
    Investigational

    Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. … It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases.

  6. Drug

    Verpasep caltespen

    go.drugbank.com/drugs/DB04959
    Investigational

    E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. … Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7.

    Synonyms: BCG65-E7, HPV 16 E7/HSP65 vaccine
  7. Drug

    Diphemanil

    go.drugbank.com/drugs/DB13720
    ApprovedVet approvedWithdrawn

  8. Drug

    Maltose

    go.drugbank.com/drugs/DB03323
    Investigational

    A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell. … AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells.

  10. Drug

    N-Acetylglucosamine

    go.drugbank.com/drugs/DB00141
    ApprovedInvestigationalNutraceutical

    The N-acetyl derivative of glucosamine.

    Synonyms: N-Acetylchitosamine, N-Acetylglucosamine