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Oxaprozin
go.drugbank.com/drugs/DB00991ApprovedOxaprozin is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingProducts: DILOX®, DURAPROX®RTA 744
go.drugbank.com/drugs/DB05920InvestigationalRTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers.
Quinethazone
go.drugbank.com/drugs/DB01325ApprovedQuinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Categories: Heterocyclic Compounds, 2-RingCrotalus adamanteus antivenin
go.drugbank.com/drugs/DB13893ApprovedIt is intravenously administered to limit systemic toxicity [FDA label]. … The eastern diamondback rattlesnake is the largest of the 32 species of rattlesnake currently recognized.
Ardeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnArdeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. … Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight of 5500 to 6500.
ASI402
go.drugbank.com/drugs/DB06373InvestigationalASI402 is a monoclonal antibody that targets an aberrantly glycosylated antigen Mucin 1. It is being investigated in cancers.
Synonyms: IMMUNOGLOBULIN G1, ANTI-(HUMAN EPISIALIN) (HUMAN-MOUSE MONOCLONAL HMFG-1 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL HMFG-1, DIMER, IMMUNOGLOBULIN G1, ANTI-(HUMAN EPISIALIN) (MOUSE MONOCLONAL HMFG-1 .GAMMA.1-CHAIN), DISULFIDE WITH MOUSE MONOCLONAL HMFG-1, DIMERPipobroman
go.drugbank.com/drugs/DB00236ApprovedAn antineoplastic agent that acts by alkylation.
Synonyms: N,N-bis-(3-bromopropionyl)-piperazine, 1,4-bis(3-bromopropionyl)piperazineCategories: Heterocyclic Compounds, 1-RingSinapultide
go.drugbank.com/drugs/DB11332ApprovedWithdrawnSinapultide (also known as KL4 peptide) is a synthetic protein used to mimic human lung surfactant protein B.[L2502] This protein has a weight of 2469.40. … [L2505] Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in preterm infants.
Cyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalIt is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Synonyms: Cyproterone 17-O-acetateMixtures: DONABELLA® 2 MG /0.035 MG, DONABELLA® 2 MG /0.035 MGDDP-225
go.drugbank.com/drugs/DB05642InvestigationalDDP225 is both a noradrenaline reuptake inhibitor and a serotonin type 3 receptor (5-HT3) antagonist. … The unique combination of noradrenaline reuptake inhibition and 5-HT3 antagonism in one orally delivered compound represents a novel approach to treating IBS-d and other functional GI diseases.
Categories: Heterocyclic Compounds, 1-Ring