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Hydracarbazine
go.drugbank.com/drugs/DB09243ExperimentalHydracarbazine is a pyridazine that has found use as an antihypertensive agent [A19790] It was once marketed in France under the tradename Normatensyl.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeOxaprotiline
go.drugbank.com/drugs/DB09307ExperimentalOxaprotiline is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. This drug was never marketed. … Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGlycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalChemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Methapyrilene
go.drugbank.com/drugs/DB04819ApprovedWithdrawnMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Nilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
MMDA
go.drugbank.com/drugs/DB01442ExperimentalIllicitMMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. … The effects of MMDA includes feelings of euphoria and warmth, as well as realistic closed-eye visuals.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AgonistsEnoximone
go.drugbank.com/drugs/DB04880ApprovedInvestigationalWithdrawnTrials were halted in the U.S., but the drug is used in various countries.
Nizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Clofibrate
go.drugbank.com/drugs/DB00636ApprovedWithdrawnA fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Hexachlorophene
go.drugbank.com/drugs/DB00756ApprovedWithdrawn(From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
International brands: E-Z scrub