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Displaying results 3541 - 3550 of 9322 in total
  1. Drug

    Fosinoprilat

    go.drugbank.com/drugs/DB14207
    Experimental

    Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.

    Categories: Agents Acting on the Renin-Angiotensin System
  2. Drug

    Imidafenacin

    go.drugbank.com/drugs/DB09262
    Investigational

    It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. … It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical.

  3. Drug

    Equilin

    go.drugbank.com/drugs/DB02187
    Experimental

    It has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.

  4. Drug

    Sorbitol

    go.drugbank.com/drugs/DB01638
    ApprovedInvestigational

    A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.

  5. Drug

    Zeaxanthin

    go.drugbank.com/drugs/DB11176
    ApprovedInvestigational

    Zeaxanthin is one of the two primary xanthophyll carotenoids contained within the retina of the eye and plays a predominant component in the central macula. … It gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries.

  6. Drug

    Lyme disease vaccine (recombinant OspA)

    go.drugbank.com/drugs/DB00045
    ApprovedWithdrawn

    Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.

  7. Drug

    Hemoglobin

    go.drugbank.com/drugs/DB04945
    ApprovedInvestigationalWithdrawn

    The respiratory protein of the red blood cells. It consists primarily of globin and heme.

  8. Drug

    Carmofur

    go.drugbank.com/drugs/DB09010
    ApprovedWithdrawn

    Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

  9. Drug

    Rosin

    go.drugbank.com/drugs/DB11165
    Approved

    It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components. … Rosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267].

  10. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.

    Synonyms: Human t-PA (residues 1-3 and 176-527)