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Displaying results 3561 - 3570 of 10000 in total
  1. Pathway

    Acylcarnitine 5-Oxodecanoylcarnitine

    smpdb.ca/view/SMP0123930
    Metabolic

    5-Oxodecanoylcarnitine is an acylcarnitine. … Once in the matrix, 5-oxodecanoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 5-oxodecanoyl-CoA and L-carnitine. 5

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  2. Pathway

    Acylcarnitine 5-Hydroxyundecanoylcarnitine

    smpdb.ca/view/SMP0123940
    Metabolic

    5-Hydroxyundecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxyundecanoyl-CoA reacts with L-carnitine to form 5-hydroxyundecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  3. Pathway

    Acylcarnitine 5-hydroxyhexadecanoylcarnitine

    smpdb.ca/view/SMP0124252
    Metabolic

    5-hydroxyhexadecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxyhexadecanoyl-CoA reacts with L-carnitine to form 5-hydroxyhexadecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  4. Pathway

    Acylcarnitine 5-hydroxyhexadecanedioylcarnitine

    smpdb.ca/view/SMP0124302
    Metabolic

    5-hydroxyhexadecanedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxyhexadecanedioyl-CoA reacts with L-carnitine to form 5-hydroxyhexadecanedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  5. Pathway

    5-Oxoprolinase Deficiency

    smpdb.ca/view/SMP0125617
    Disease

    5-Oxoprolinase deficiency, also called OPLAHD, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of glutathione metabolism caused by a defective 5-oxoprolinase. 5-Oxoprolinase … This disorder is characterized by a large accumulation of 5-oxoproline in the urine.

    Drugs: Glutamic acid · Glutathione · Glycine · Cysteine · Alanine · ATP +5 more
    Enzymes: 5-oxoprolinase
  6. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … [A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately

    Mixtures: CEFAZIME FOR INJECTION 1 g/vial, ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADETCategories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Carbinoxamine

    go.drugbank.com/drugs/DB00748
    Approved

    This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many

    Mixtures: PHILDEX 2Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Alitretinoin

    go.drugbank.com/drugs/DB00523
    Approved

    Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. … An important regulator of gene expression during growth and development, and in neoplasms.

    Mixtures: Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05%Categories: Vitamin A, P-glycoprotein substrates
  9. Drug

    Peginterferon alfa-2a

    go.drugbank.com/drugs/DB00008
    ApprovedInvestigational

    Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) no longer recommend Peginterferon alfa

    Categories: Compounds used in a research, industrial, or household setting, Interferon Type IProducts: PEGASYS 135 MCG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ŞIRINGA, 1 ADET, PEGASYS 135 MCG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ŞIRINGA, 4 ADET
  10. Drug

    Anagrelide

    go.drugbank.com/drugs/DB00261
    ApprovedInvestigational

    [L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997.[A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. … Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: ANAGRELID RATIO 1 MG, Anagrelid Nordic 1 mg Tabletten