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Displaying results 351 - 360 of 7535 in total
  1. Drug

    Isopropyl myristate

    go.drugbank.com/drugs/DB13966
    Approved

    [A178078] At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse [A32333, L1964, L1966]. … Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.

  2. Indication

    Anorexia

    go.drugbank.com/conditions/DBCOND0004522
    Drugs: Dronabinol · Hemicellulase · Itopride · Megestrol acetate
    Synonyms: No appetite
  3. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178948] The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults.

    Products: NOR TENZ
  4. Target

    Esterase EstA

    go.drugbank.com/bio_entities/BE0003982
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents. … Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes

    Polypeptides: Esterase EstASynonyms: Autotransporter esterase EstA
  5. Target

    Cocaine esterase

    go.drugbank.com/bio_entities/BE0004712
    EnzymeHumans

    Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443). Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (P...

    Polypeptides: Cocaine esterase
  6. Target

    Esterase, putative

    go.drugbank.com/bio_entities/BE0009247
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Esterase, putative
  7. Drug

    Cefprozil

    go.drugbank.com/drugs/DB01150
    ApprovedInvestigational

    Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.

    Products: Nu-cefprozil
  8. Target

    Nitric oxide synthase, inducible

    go.drugbank.com/bio_entities/BE0000005
    TargetEnzymeHumans

    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7504305, PubMed:7531687, PubMed:7544004, PubMed:7682706). … In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).

    Synonyms: Inducible NO synthase
  9. Drug

    Nicotinamide Mononucleotide

    go.drugbank.com/drugs/DB03227
    Investigational

    A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]

    Products: Reus Nr
  10. Drug

    N-[2-(1-Formyl-2-Methyl-Propyl)-1-(4-Piperidin-1-Yl-but-2-Enoyl)-Pyrrolidin-3-Yl]-Methanesulfonamide

    go.drugbank.com/drugs/DB03890
    Experimental

    Synonyms: N-[2-(1-Formyl-2-Methyl-Propyl)-1-(4-Piperidin-1-Yl-but-2-Enoyl)-Pyrrolidin-3-Yl]-Methanesulfonamide