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Perampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalIt is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. … The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™.
Products: FYCOMPA FILM-COATED TABLET 10MG, Fycompa 10mg Film-coated TabletsCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigationalCladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment multiple sclerosis.[A263718]
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Mavenclad 10mg Tablets, MAVENCLAD TABLET 10MGSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalIt has an identical primary protein structure to endogenous human growth hormone.[A228188] Recombinant HGH has been commercially available since 1985 after its development by Genentech. … [Somatrem] was the first available recombinant HGH and was largely replaced by somatropin, another form of recombinant HGH.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im Sc, Nutropin - Kit Pws(10mg) & Liq(10ml) Im ScCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalEsomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … _), reduced absorption of micronutrients such as iron and B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis and bone fractures later in life.
Mixtures: VIMOVO 500MG/20MG MODIFIED-RELEASE TABLETS, Naproxen and esomeprazole magnesiumCategories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Alimentary Tract and MetabolismChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalOne of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.
Mixtures: IBUCOLD PLUS 100MG+15MG+1MG/5ML ŞURUP, 100 ML SISE, Ana-kit (2mg/tab Orl, 1mg/ml Liq Sc Im)Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), an important vasodilator that decreases blood pressure [A175321]. … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_.
Mixtures: Exforge HCT Tablet 10mg/160mg/25mg, Amlodipin/Valsartan/HCT +pharma 10mg/160mg/25mg FilmtablettenCategories: losartan and amlodipine, ramipril and amlodipineCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
Mixtures: Satohap Cool and Hot Pads, DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAKCategories: Basic Lotions and Liniments, Capsaicin and Similar AgentsDicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigationalDicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder … and irritable bowel syndrome.
Categories: Alimentary Tract and MetabolismProducts: Protylol Tab 20mg, Bentylol Tablet 20mgOxazepam
go.drugbank.com/drugs/DB00842Approvedas compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism. … [A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: Serax Tab 15mg, Serax Tablets 15mgPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalIt is used as an ointment base, topical protectant, and lubricant.
Mixtures: Renuu NL, A and D First AidCategories: Basic Ointments and Protectants