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Quinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalQuinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Oxalic Acid
go.drugbank.com/drugs/DB03902ExperimentalA strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. … It is used as an analytical reagent and general reducing agent. [PubChem]
Categories: Compounds used in a research, industrial, or household settingZatebradine
go.drugbank.com/drugs/DB21228ExperimentalZatebradine is a small molecule drug. The usage of the INN stem '-bradine' in the name indicates that Zatebradine is a bradycardic agent. Zatebradine has a monoisotopic molecular weight of 456.26 Da.
Categories: Compounds used in a research, industrial, or household settingRilapladib
go.drugbank.com/drugs/DB05119InvestigationalIt is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques. … Rilapladib is the third genomics-derived small molecule drug arising from the Human Genome Sciences-GlaxoSmithKline collaboration to enter clinical development.
Cellobiose
go.drugbank.com/drugs/DB02061ExperimentalA disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose. [PubChem]
Categories: Compounds used in a research, industrial, or household settingLeronlimab
go.drugbank.com/drugs/DB05941InvestigationalLeronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn.[L12684] It was first described in the literature in 2001. … [A3922] This antibody binds to CCR5, which may be useful in treating HIV, cancers, and severely ill COVID-19 patients.[A192846,A192858,L12684]
Axitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigational[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).
Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideCategories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexPropacetamol
go.drugbank.com/drugs/DB09288Investigational[A7892] It is not available in the United States but this prodrug has been widely used in other countries such as France since 1985.[L1505] … Propacetamol is a parenteral formulation of paracetamol and thus, it is a prodrug that is completely hydrolyzed to paracetamol.
Pyrimethamine
go.drugbank.com/drugs/DB00205ApprovedInvestigationalVet approvedOne of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
NV-52
go.drugbank.com/drugs/DB05673ExperimentalNV-52 is an investigational synthetic flavonoid thromboxane synthase (TXS) inhibitor developed for the maintenance of remission in inflammatory bowel disease.