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Displaying results 3611 - 3620 of 3889 in total
  1. Drug

    Orludodstat

    go.drugbank.com/drugs/DB21498
    Investigational

    The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor.

  2. Drug

    Lepzacitinib

    go.drugbank.com/drugs/DB21646
    Investigational

    The usage of the INN stem '-citinib' in the name indicates that Lepzacitinib is a Janus kinase inhibitor.

  3. Drug

    Luvometinib

    go.drugbank.com/drugs/DB21696
    Investigational

    The usage of the INN stem '-tinib' in the name indicates that Luvometinib is a tyrosine kinase inhibitor.

  4. Drug

    Pebezertinib

    go.drugbank.com/drugs/DB21705
    Investigational

    The usage of the INN stem '-ertinib' in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) inhibitor.

  5. Drug

    Inlexisertib

    go.drugbank.com/drugs/DB21713
    Investigational

    The usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor.

  6. Drug

    Racemetyrosine

    go.drugbank.com/drugs/DB16306
    Investigational

    Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).

    Synonyms: Sm-88 component racemetyrosine
  7. Drug

    Gonadorelin

    go.drugbank.com/drugs/DB00644
    ApprovedInvestigationalVet approved

    Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormon...

    Categories: Sex Hormones and Insulins
  8. Drug

    Polythiazide

    go.drugbank.com/drugs/DB01324
    Approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)

    Categories: Genito Urinary System and Sex Hormones
  9. Target

    Proteasome subunit alpha type-2

    go.drugbank.com/bio_entities/BE0003911
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C3
  10. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-depende...

    Synonyms: Progesterone receptor complex p23