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Acylcarnitine 5-Dodecenoylcarnitine
smpdb.ca/view/SMP0124004Metabolic5-Dodecenoylcarnitine is an acylcarnitine. … Once in the matrix, 5-dodecenoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 5-dodecenoyl-CoA and L-carnitine. 5-Dodecenoyl-CoA
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 5-Hydroxydodecanoylcarnitine
smpdb.ca/view/SMP0124095Metabolic5-Hydroxydodecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydodecanoyl-CoA reacts with L-carnitine to form 5-hydroxydodecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine 5-Hydroxytetradecanedioylcarnitine
smpdb.ca/view/SMP0124219Metabolic5-Hydroxytetradecanedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxytetradecanedioyl-CoA reacts with L-carnitine to form 5-hydroxytetradecanedioylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Tenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigationala novel alternative in the treatment of IBS-C. … Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XPHOZAH 10 mg, XPHOZAH 20 mgTucatinib
go.drugbank.com/drugs/DB11652ApprovedInvestigationalTucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer. … It was developed by Seattle Genetics and approved by the FDA on April 17, 2020.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: TUKYSA 50 mg film-coated tablets, TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mgCiprofibrate
go.drugbank.com/drugs/DB09064ApprovedInvestigationalWithdrawnProducts: GIABRI® 100 MG TABLETAS, HIPERLIPEN ® 100 MG TABLETASelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigationalSelinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. … Selinexor, in combination with [bortezomib] and [dexamethasone], is currently approved for the treatment of multiple myeloma, a type of cancer formed from antibody-producing plasma cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 8 TABLET, Nexpovio 20 mg Film Kaplı Tablet, 12 TABLETBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Mixtures: M-end Wc, M-end PECategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingPimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADETEtravirine
go.drugbank.com/drugs/DB06414ApprovedInvestigationalOn March 26, 2012, approval was extended for use in treatment-experienced pediatric patients 6 to 18 years of age, weighing at least 16 kg. … of rashes in patients taking etravirine, lead to a modification of etravirine's monograph.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: INTELENCE TABLET 200 MG, INTELENCE 100 MG TABLETS